Karen is a biostatistician known for her research on aging and aging-related frailty. She is the Hurley Dorrier Professor of Biostatistics at the Johns Hopkins Bloomberg School of Public Health. Bandeen-Roche earned a master’s degree and PhD in operations research from Cornell University in 1988 and 1990, respectively. She has worked at Johns Hopkins since 1990, and became the Hurley Dorrier Professor and was Chair from 2008-2024.Dr. Bandeen-Roche’s primary research area is the development, implementation, and application of models for problems which include underlying or unobservable processes of interest. In recent years, she has primarily been interested the application of underlying variable methods in epidemiologic and psycho-social research. Her other areas of statistical research include the study of classification and variance structure and multivariate survival analysis. Gerontology is the scientific area in which she feels most deeply invested; having participated in population research on aging for more than a decade, was named a Brookdale National Fellow, and co-directed a training program in the Biostatistics and Epidemiology of Aging.